Direct Purification from Unclarified Feed Streams
SMART Chromatography™
SMART Chromatography™ enables fast, scalable purification of proteins, antibodies, and tagged biomolecules — directly from cell-containing feed streams. No clarification, no centrifugation. Each column is packed with large-particle agarose resin for low backpressure and high flow rates, using ligands tailored for your application.
Alternative SMART Chromatography™ formats may offer better alignment with specific purification requirements:
Ion Exchange Columns
Affinity Columns
Hydrophobic Interaction Columns
SMART Chromatography™ DEAE
SMART Chromatography™ column packed with Weak Anion Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ column packed with Strong Anion Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ CM Boost
SMART Chromatography™ column packed with Weak Cation Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ DEAE
SMART Chromatography™ column packed with Weak Anion Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ SP
SMART Chromatography™ column packed with Strong Cation Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ SP Boost
SMART Chromatography™ column packed with Strong Cation Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ CM
SMART Chromatography™ column packed with Weak Cation Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ DEAE Boost
SMART Chromatography™ column packed with Weak Anion Exchange Agarose Resin. Specifically designed for SMART Chromatography™ ion exchange separation.
SMART Chromatography™ Protein A Elevate
SMART Chromatography™ FPLC column packed with NaOH-tolerant recombinant Protein A Agarose Resin.Specifically designed for SMART Chromatography™ to purify immunoglobulins via their selective affinity to Protein A.
SMART Chromatography™ Ni-NTA
SMART Chromatography™ FPLC column packed with Ni-NTA Agarose Resin.Specifically designed for SMART Chromatography™ IMAC protein purification via their selective affinity to chelated nickel.
SMART Chromatography™ NTA (metal-free)
SMART Chromatography™ FPLC column packed with NTA Agarose Resin.Specifically designed for SMART Chromatography™ IMAC protein purification via their selective affinity to chelated metal ions²⁺.
SMART Chromatography™ Butyl
SMART Chromatography™ Butyl is a column packed with large diameter beaded agarose resin immobilized with butyl ligand. Specifically designed for SMART Chromatography™ hydrophobic interaction exchange separation.
SMART Chromatography™ Phenyl
SMART Chromatography™ Phenyl is a column packed with large diameter beaded agarose resin immobilized with phenyl ligand. Specifically designed for SMART Chromatography™ hydrophobic interaction exchange separation.
SMART Chromatography™ FPLC column packed with Aldehyde-activated Agarose Resin. Specifically designed for SMART Chromatography™ with custom-tailored resin.