High-Purity Phosphoramidites and Solid Supports for Oligonucleotide Synthesis
High-Quality Phosphoramidites and Solid Supports for Reliable Oligonucleotide Synthesis
BioInnovas offers a comprehensive portfolio of phosphoramidites, solid supports, and CPG materials to meet the diverse needs of oligonucleotide synthesis—from standard DNA/RNA production to advanced modified and labeled constructs.
Phosphoramidites Portfolio
|
Type |
Application |
Key Features |
|---|---|---|
|
Standard DNA & RNA |
Oligonucleotide synthesis |
High purity, low moisture, ready-to-use formats |
|
2′‑O‑Methyl (2′‑OMe) |
siRNA, antisense oligos |
Nuclease resistance, enhanced duplex stability |
|
2′‑MOE |
Therapeutic and diagnostic applications |
Improved pharmacokinetics and target affinity |
|
2′‑Fluoro |
RNA-based therapeutics |
High thermal stability, enhanced RNA structure |
|
5′‑Amino Modifier |
Conjugation and labeling |
Reactive primary amine for downstream coupling |
|
Reverse Amidites |
Specialized synthesis workflows |
Enables reverse-direction synthesis |
|
Dye- or Linker-Modified Amidites |
Probes, qPCR, imaging |
Fluorescent dyes, quenchers, and custom linkers |
Solid Supports (CPGs and PS)
|
Type |
Application |
Key Features |
|---|---|---|
|
Nucleoside-Linked CPG |
DNA/RNA synthesis platforms |
High loading capacity, consistent coupling efficiency |
|
Universal Solid Support |
Versatile oligo synthesis |
Sequence-independent, ideal for high-throughput use |
|
Dye- or Modifier-Linked CPG |
Probes, labeled oligonucleotides |
Integrated dyes, spacers, or functional groups |
|
Polystyrene (PS) based Support |
Large oligonucleotides |
High loading capacity, ideal for large oligos |
Custom Services
In addition to our standard portfolio, BioInnovas offers custom amidite synthesis and tailored CPG solid supports to meet specific oligonucleotide synthesis needs.
Whether you require unique modifiers, specialized linkers, custom pore sizes, or bulk packaging up to 10 kg, our team works closely with you to deliver optimized solutions for research, diagnostics, or large-scale manufacturing.