From Synthesis to Purification: Complete Solutions for Oligonucleotide Production
Deblocking / Detritylation
High-performance deblocking reagents for oligonucleotide synthesis. Our formulations deliver precise and efficient detritylation under diverse synthesis conditions. Choose from dichloroacetic or trichloroacetic acid in toluene or methylene chloride. Options include low water content formulations and reagents optimized for sensitive protocols or automated systems like ÄKTA oligopilot. Ensure clean, consistent deblock steps with every cycle.
5% Dichloroacetic Acid in Toluene (for ÄKTA oligopilot™)
5% Dichloroacetic Acid in Toluene is a high-purity deblocking reagent optimized for ÄKTA oligopilot™ systems, enabling efficient 5′-DMT group removal during automated DNA and RNA oligonucleotide synthesis.
3% Dichloroacetic Acid in Methylene Chloride
3% Dichloroacetic Acid in Methylene Chloride is a high-purity deblocking reagent for efficient removal of the 5′-DMT protecting group during automated DNA and RNA oligonucleotide synthesis.
Hyacinth Deblocking Reagent 3% Dichloroacetic Acid in Toluene (water content <30 ppm)
Hyacinth Deblocking Reagent is a high-purity 3% Dichloroacetic Acid in Toluene solution with <30 ppm water, designed for efficient 5′-DMT group removal during large-scale automated DNA and RNA oligonucleotide synthesis.