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NC-0402

CHF 0.00

Hyacinth Deblocking Reagent 3% Dichloroacetic Acid in Toluene (water content <30 ppm)

Hyacinth Deblocking Reagent is a high-purity 3% Dichloroacetic Acid in Toluene solution with <30 ppm water, designed for efficient 5′-DMT group removal during large-scale automated DNA and RNA oligonucleotide synthesis.

SKU: NC-0402 Category:

Description

Deblocking / Detritylation

Deblocking solutions, used for the cleavage of the 5‘-DMTr group at the last building block of nucleotide chain, can consist either of dichloroacetic or trichloroacetic acid in dichloromethane or toluene. Our Hyacinth Deblocking solution (3 % dichloroacetic acid in toluene at < 30 ppm water) is applicable for the syntheses of high quality, large scale oligonucleotides.

Additional information

Pack Size

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Safety Information

Hazard Classifications

  • Flammable liquid, Category 2 (Flam. Liq. 2)

  • Aspiration hazard, Category 1 (Asp. Tox. 1)

  • Skin irritation, Category 2 (Skin Irrit. 2)

  • Serious eye damage/eye irritation, Category 1 (Eye Dam. 1)

  • Specific target organ toxicity – single exposure, Category 3 (STOT SE 3)

  • Carcinogenicity, Category 2 (Carc. 2)

  • Reproductive toxicity, Category 1B (Repr. 1B)

  • Specific target organ toxicity – repeated exposure, Category 2 (STOT RE 2)

  • Hazardous to the aquatic environment, Category 3 (Aquatic Chronic 3)

Hazard Statements

  • H225: Highly flammable liquid and vapor.

  • H304: May be fatal if swallowed and enters airways.

  • H315: Causes skin irritation.

  • H318: Causes serious eye damage.

  • H336: May cause drowsiness or dizziness.

  • H351: Suspected of causing cancer .

  • H360FD: May damage fertility. May damage the unborn child.

  • H373: May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure .

  • H410: Very toxic to aquatic life with long lasting effects.

Precautionary Statements

  • P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

  • P273: Avoid release to the environment.

  • P280: Wear protective gloves/protective clothing/eye protection/face protection.

  • P301+P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

  • P331: Do NOT induce vomiting.

Signal Word

Danger

WGK

WGK 2

Storage Class Code

3 – Flammable liquids

Transport Information

ADR, RID (road and rail): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II

IATA-DGR (air transport): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II

IMDG Code (sea transport): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II

Downloads

Material safety data sheet
Product specification sheet
Synthesis Reagents, Catalog