Additional information
| Pack Size |
|---|
NC-0409
CHF 0.00
10% Dichloroacetic Acid in Toluene
Description
Deblocking / Detritylation
Deblocking solutions, used for the cleavage of the 5‘-DMTr group at the last building block of nucleotide chain, can consist either of dichloroacetic or trichloroacetic acid in dichloromethane or toluene. Our Hyacinth Deblocking solution (3 % dichloroacetic acid in toluene at < 30 ppm water) is applicable for the syntheses of high quality, large scale oligonucleotides.
Safety Information
Hazard Classifications
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Flammable liquid, Category 2 (Flam. Liq. 2)
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Aspiration hazard, Category 1 (Asp. Tox. 1)
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Skin irritation, Category 2 (Skin Irrit. 2)
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Serious eye damage/eye irritation, Category 1 (Eye Dam. 1)
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Specific target organ toxicity – single exposure, Category 3 (STOT SE 3)
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Carcinogenicity, Category 2 (Carc. 2)
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Reproductive toxicity, Category 1B (Repr. 1B)
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Specific target organ toxicity – repeated exposure, Category 2 (STOT RE 2)
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Hazardous to the aquatic environment, Category 3 (Aquatic Chronic 3)
Hazard Statements
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H225: Highly flammable liquid and vapor.
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H304: May be fatal if swallowed and enters airways.
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H315: Causes skin irritation.
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H318: Causes serious eye damage.
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H336: May cause drowsiness or dizziness.
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H351: Suspected of causing cancer .
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H360FD: May damage fertility. May damage the unborn child.
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H373: May cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure .
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H410: Very toxic to aquatic life with long lasting effects.
Precautionary Statements
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P202: Do not handle until all safety precautions have been read and understood.
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P273: Avoid release to the environment.
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P280: Wear protective gloves/protective clothing/eye protection/face protection.
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P301+P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor/…
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P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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P331: Do NOT induce vomiting.
Signal Word
Danger
WGK
WGK 2
Storage Class Code
3 – Flammable liquids
Transport Information
ADR, RID (road and rail): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II
IATA-DGR (air transport): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II
IMDG Code (sea transport): UN2924 FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Solution of Dichloroacetic Acid in Toluene), 3(8), II
