CHF 0.00
3% Dichloroacetic Acid in Methylene Chloride is a high-purity deblocking reagent for efficient removal of the 5′-DMT protecting group during automated DNA and RNA oligonucleotide synthesis.
Deblocking solutions, used for the cleavage of the 5‘-DMTr group at the last building block of nucleotide chain, can consist either of dichloroacetic or trichloroacetic acid in dichloromethane or toluene. Our Hyacinth Deblocking solution (3 % dichloroacetic acid in toluene at < 30 ppm water) is applicable for the syntheses of high quality, large scale oligonucleotides.
| Pack Size | 2.5L, GL45 thread, 4L, GL45 thread or 38-430 thread, Bulk request |
|---|
Skin irritation, Category 2 (Skin Irrit. 2)
Serious eye damage/eye irritation, Category 1 (Eye Dam. 1)
Specific target organ toxicity – single exposure, Category 3 (STOT SE 3)
Carcinogenicity, Category 2 (Carc. 2)
Reproductive toxicity, Category 1B (Repr. 1B)
Hazardous to the aquatic environment, Category 1 (Aquatic Acute 1)
H315: Causes skin irritation.
H318: Causes serious eye damage.
H336: May cause drowsiness or dizziness.
H351: Suspected of causing cancer .
H360FD: May damage fertility. May damage the unborn child.
H400: Very toxic to aquatic life.
P202: Do not handle until all safety precautions have been read and understood.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of water/…
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+P313: IF exposed or concerned: Get medical advice/attention.
Danger
WGK 2
6.1D
ADR, RID (road and rail): UN2922 CORROSIVE LIQUID, TOXIC, N.O.S. (Solution of Dichloroacetic acid in Methylene chloride), 8(6.1), III
IATA-DGR (air transport): UN2922 CORROSIVE LIQUID, TOXIC, N.O.S. (Solution of Dichloroacetic acid in Methylene chloride), 8(6.1), III
IMDG Code (sea transport): UN2922 CORROSIVE LIQUID, TOXIC, N.O.S. (Solution of Dichloroacetic acid in Methylene chloride), 8(6.1), III
