High-Purity Capping Reagents for Accurate DNA and RNA Oligonucleotide Synthesis
Capping Solutions
Capping reagents are essential for blocking unreacted 5′ hydroxyl groups during phosphoramidite oligonucleotide synthesis, preventing the formation of n minus 1 sequences and ensuring product integrity. emp BIOTECH offers high-purity Capping Mix A and B formulations, including ultramild and platform-specific variants, designed for compatibility with a wide range of DNA and RNA synthesis workflows. Choose from acetonitrile, THF, pyridine, or lutidine based blends to match your protocol and maintain consistent synthesis fidelity from start to finish.
5-Benzylthiotetratzole (BTT) Crystal
5-Benzylthiotetrazole (BTT) Crystal, CAS 21871-47-6, is a high-performance activator used in automated DNA and RNA oligonucleotide synthesis to enable efficient phosphoramidite coupling with high yields and low n–1 impurity levels.
0.6 M 5-Ethylthiotetrazole (ETT) in anhydrous Acetonitrile
0.6 M 5-Ethylthiotetrazole (ETT) in anhydrous acetonitrile is a high-efficiency activator for phosphoramidite coupling in DNA and RNA oligonucleotide synthesis.
ETT Crystal (5-Ethylthiotetrazole)
ETT Crystal (5-Ethylthiotetrazole, CAS 89797-68-2) is used as a high-efficiency activator for phosphoramidite coupling in automated DNA and RNA oligonucleotide synthesis.
0.5 M 5-Ethylthiotetrazole (ETT) in anhydrous Acetonitrile
0.5 M 5-Ethylthiotetrazole (ETT) in anhydrous acetonitrile is a high-efficiency activator for phosphoramidite coupling in automated DNA and RNA oligonucleotide synthesis. It ensures fast reaction kinetics, high coupling yields, and minimal n–1 impurities—ideal for use with TBDMS, TOM®, and ACE® amidites across a wide range of synthesis platforms.
0.5 M 4,5-Dicyanoimidazole (DCI) in anhydrous Acetonitrile
4,5-Dicyanoimidazole (DCI) is an efficient activator for use in chemical synthesis of DNA.
1.0 M DCI Activator with NMI
4,5-Dicyanoimidazole (DCI) is an efficient activator for use in chemical synthesis of DNA.