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NC-0101

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5-Benzylthiotetratzole (BTT) Crystal

5-Benzylthiotetrazole (BTT) Crystal, CAS 21871-47-6, is a high-performance activator used in automated DNA and RNA oligonucleotide synthesis to enable efficient phosphoramidite coupling with high yields and low n–1 impurity levels.

SKU: NC-0101 Categories: ,

Description

Hyacinth BMT activator (also known as 5-Benzylmercapto-1H-tetrazole or BTT) demonstrates important advantages in the syntheses of oligonucleotides:

  • Coupling efficiencies of 99 % with impeccable quality
  • Lower percentage of n-1 sequences
  • Dramatic reduction of coupling times to under 3 minutes in RNA syntheses
  • Efficient RNA synthesis using 50 % or less TBDMS, TOM® or ACE® monomer
  • Excellent batch to batch consistency for reproducible and stable oligo production

Additional information

Pack Size

,

Specification

Safety Information

 
Hazard Classifications

  • Skin irritation, Category 2 (Skin Irrit. 2)

  • Serious eye damage/eye irritation, Category 1 (Eye Dam. 1)

  • Specific target organ toxicity – single exposure, Category 3 (STOT SE 3)

Hazard Statements

  • H315: Causes skin irritation.

  • H318: Causes serious eye damage.

  • H335: May cause respiratory irritation.

Precautionary Statements

  • P261: Avoid breathing dust/fume/gas/mist/vapors/spray.

  • P280: Wear protective gloves/protective clothing/eye protection/face protection.

  • P302+P352: IF ON SKIN: Wash with plenty of water/…

  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Signal Word

Danger

WGK

WGK 3

Storage Class Code

13 – Non-flammable solids in non-flammable package

Transport Information

ADR, RID (road and rail): Not dangerous goods

IATA-DGR (air transport): Not dangerous goods

IMDG Code (sea transport): Not dangerous goods

Downloads

Material safety data sheet
Product specification sheet
Synthesis Reagents, Catalog