Description
High-Resolution Anion Exchange Chromatography with 15 µm Polystyrene Resin
Zetarene Q15 from emp BIOTECH is a strong anion exchange resin engineered for high-resolution purification of negatively charged biomolecules, especially oligonucleotides. The resin consists of uniformly shaped 15 µm beads based on highly cross-linked polystyrene/divinylbenzene (PS-DVB), derivatized with quaternary ammonium groups. Its fine particle size and porous surface support sharp peak separation with high binding capacity and excellent pressure-flow characteristics, even at high linear velocities.
Zetarene Q15 is chemically stable, pH-resistant, and pressure-tolerant, making it ideal for demanding ion exchange chromatography (IEX) workflows at analytical or preparative scale. Available in bulk or pre-packed column formats, it ensures scalable performance with minimal backpressure and high reproducibility.
Performance Highlights
- Uniform 15 µm particle size for high-resolution separations
- ≥ 0.08 mmol Cl⁻/mL ionic capacity
- ≥ 1800 cm/h linear flow rate under pressure
- Porous surface for high binding capacity
- Low backpressure, even at high flow rates
- pH-stable from 2 to 12
Specifications
- Matrix: Highly cross-linked polystyrene/divinylbenzene (PS-DVB)
- Functional Group: Quaternary ammonium (strong anion exchanger)
- Particle Size: ~15 µm
- Ionic Capacity: ≥ 0.08 mmol Cl⁻/mL
- Maximum Linear Flow Rate: ≥ 1800 cm/h (10 mm ID, 20 cm bed)
- pH Stability: 2 – 12
- Format: Bulk resin (pre-packed columns on request)
Applications
- Oligonucleotide purification
- High-resolution ion exchange chromatography
- Nucleic acid analysis
- Polishing steps in downstream bioprocessing
Why Choose Zetarene Q15?
Zetarene Q15 combines fine particle size, porous surface area, and robust polystyrene chemistry to deliver high-resolution separations at scale. Its consistent performance under pressure and resistance to chemical degradation make it a reliable choice for oligonucleotide purification and other applications requiring sharp resolution, high flow rates, and scalability.
