Description
Streamlined HIC Separation Using Butyl Ligand SMART™ Resin
ZetaCell Butyl from emp BIOTECH is a hydrophobic interaction chromatography (HIC) resin engineered for robust and scalable protein purification using SMART™ Chromatography. The resin features large, cross-linked 250 µm agarose beads functionalized with butyl ligands, enabling salt-dependent purification of hydrophobic biomolecules under mild conditions.
Thanks to the proprietary SMART™ resin architecture, ZetaCell Butyl supports unhindered flow of cell-containing feedstocks and minimizes clogging or backpressure in packed bed formats. It is ideal for integration into continuous or batch HIC workflows where consistency, scalability, and compatibility with high-throughput systems are essential.
Performance Highlights
- Large 250 µm cross-linked agarose beads
- Functionalized with aliphatic butyl (C₄H₉) ligand
- Designed for salt-driven retention and elution
- Compatible with SMART™ Chromatography platforms
- Excellent flow properties, even with cell-containing feeds
- Operates efficiently in preparative and process-scale HIC
Specifications
- Matrix: Cross-linked beaded agarose
- Ligand: Butyl (C₄H₉)
- Bead Diameter: Average 250 µm
- Storage Buffer: 20% ethanol
Applications
- Hydrophobic interaction chromatography (HIC)
- Purification of hydrophobic proteins and biomolecules
- Scalable downstream processing
- Separation of antibodies, enzymes, or protein isoforms
Why Choose ZetaCell Butyl?
ZetaCell Butyl offers excellent separation of hydrophobic targets under mild, salt-controlled conditions. Its robust bead design and SMART™-compatible format enable high-throughput purification from complex feedstocks without compromising flow rate or column performance—ideal for modern bioprocessing demands.
