Description
High-Capacity Strong Anion Exchange Resin for Biomolecule Separation
Zetadex-50 QAE from emp BIOTECH is a strong anion exchange resin based on a beaded composite of cross-linked dextran, optimized for reliable purification of negatively charged biomolecules. Functionalized with quaternary aminoethyl groups, this resin offers high ionic capacity and excellent performance for ion exchange chromatography (IEX) in both small- and large-scale applications.
With a particle size range of 40–120 µm and high functional group density, Zetadex-50 QAE enables efficient separation of nucleic acids, proteins, and other anionic species under varying process conditions. The matrix maintains chemical stability and resolution even at high flow rates.
Performance Highlights
- Strong anion exchange resin for negatively charged biomolecules
- Ionic capacity: 2.6–3.4 mmol Cl⁻/g
- Functional group: Quaternary aminoethyl
- Particle size: 40–120 µm
- Maximum flow rate: > 50 cm/h
- High chemical stability across a wide pH range
Specifications
- Matrix: Cross-linked dextran
- Bead size (dry): 40–120 µm
- Ion exchange type: Strong anion exchange (AEX)
- Ion exchange group: Quaternary aminoethyl
- Ionic capacity: 2.6–3.4 mmol Cl⁻/g
- Recommended pH stability: 2–14 (short term), 3–12 (long term)
Applications
- Ion exchange chromatography (IEX)
- Purification of nucleic acids and negatively charged proteins
- Buffer exchange and polishing steps
- Process-scale and research-scale separations
Why Choose Zetadex-50 QAE?
Zetadex-50 QAE delivers high binding capacity and robust chemical performance in strong anion exchange workflows. Its optimized particle size and high ligand density enable reproducible, scalable purification of biomolecules across diverse buffer systems and purification goals. Ideal for demanding downstream processes involving nucleic acids or acidic proteins.
