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NC-0503

CHF 0.00

0.02 M Iodine in THF / Pyridine / Water (V / V / V = 66 / 22 / 12)

SKU: NC-0503 Category:

Description

Oxidizer solutions promote the oxidation of trivalent phosphotriester into pentavalent phosphate triester using iodine as a mild oxidizing agent. They are available in standard 0.02 M and 0.05 M iodine concentrations with different mixtures of Tetrahydrofuran, pyridine and water. Custom mixtures are also available. The Hyacinth Oxidizer solution [0.05 M iodine in pyridine / water (V / V = 90 : 10)] is applicable for the synthesis of high quality, large-scale oligonucleotides.

Additional information

Pack Size

,

Safety Information

Hazard Classifications

  • Flammable liquid, Category 2 (Flam. Liq. 2)

  • Acute Toxicity, Category 4 (Acute Tox. 4)

  • Skin irritation, Category 2 (Skin Irrit. 2)

  • Eye irritation, Category 2 (Eye Irrit. 2)

  • Specific target organ toxicity – single exposure, Category 3 (STOT SE 3)

  • Carcinogenicity, Category 2 (Carc. 2)

Hazard Statements

  • H225: Highly flammable liquid and vapour.

  • H302+H312+H332: Harmful if swallowed, in contact with skin or if inhaled.

  • H315: Causes skin irritation.

  • H319: Causes serious eye irritation.

  • H335: May cause respiratory irritation.

  • H351: Suspected of causing cancer .

  • EUH019: May form explosive peroxides.

Precautionary Statements

  • P202: Do not handle until all safety precautions have been read and understood.

  • P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

  • P301+P312: IF SWALLOWED: Call a POISON CENTER/doctor/… if you feel unwell.

  • P303+P361+P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].

  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

  • P308+P313: IF exposed or concerned: Get medical advice/attention.

Signal Word

Danger

WGK

WGK 2

Storage Class Code

3 – Flammable liquids

Transport Information

ADR, RID (road and rail): UN1993 FLAMMABLE LIQUID, N.O.S. (Mixture of Iodine in Tetrahydrofuran, Pyridine and Water), 3, II

IATA-DGR (air transport): UN1993 FLAMMABLE LIQUID, N.O.S. (Mixture of Iodine in Tetrahydrofuran, Pyridine and Water), 3, II

IMDG Code (sea transport): UN1993 FLAMMABLE LIQUID, N.O.S. (Mixture of Iodine in Tetrahydrofuran, Pyridine and Water), 3, II

Downloads

Material safety data sheet
Product specification sheet
Synthesis Reagents, Catalog