Description
High-efficiency purification and desalting of nucleic acids, proteins, and nanoparticles
CentriPure 10 – Z50M from emp BIOTECH is a gravity-driven gel filtration column designed for the fast and effective removal of low-molecular-weight contaminants from nucleic acids, proteins, antibodies, and nanoparticles. Optimized for 1 mL sample volumes, this column streamlines workflows in molecular biology, biochemistry, and nanotechnology by offering rapid desalting, buffer exchange, and post-synthesis cleanup.
Pre-packed with Zetadex-50, a cross-linked beaded dextran size-exclusion resin, CentriPure 10 efficiently separates small molecules like salts, dyes, haptens, ammonia, and biotin from larger target molecules. With >99.99% removal of low-MW impurities and >85% recovery of proteins and oligonucleotides (>25 kDa or >20 bp), it ensures clean and reproducible sample preparation without the need for centrifugation or vacuum filtration.
Performance Highlights
- >99.99% removal of low-molecular-weight contaminants
- >85% recovery of nucleic acids and proteins
- ~1.5-fold sample dilution
- <15-minute processing time
- Gravity flow operation – no centrifugation or vacuum needed
Specifications
- Resin: Zetadex-50 (50–150 µm particle size)
- Sample volume: 1.0 mL
- Format: Individual hydrated column
Applications
- DNA/RNA desalting and buffer exchange
- Antibody and protein purification
- Removal of labeling reagents and additives
- Nanoparticle sample cleanup
Why Choose CentriPure?
CentriPure 10 – Z50M delivers speed, simplicity, and reproducibility, making it a powerful alternative to time-intensive dialysis or ultrafiltration. Ready to use with minimal setup, this compact column empowers scientists to prepare samples with precision and confidence for downstream applications.
