Description
High-throughput desalting and DyeDeoxy removal for DNA sequencing workflows
The CentriPure 96 Gel Filtration Plate with 1000 µL well volume from emp BIOTECH is a ready-to-use solution for rapid, reproducible cleanup of dye terminators and low molecular weight impurities in high-throughput DNA sequencing workflows. Precision-packed with Zetadex-50SF, a superfine cross-linked dextran resin, this 96-well format enables simultaneous processing of up to 96 samples with excellent reproducibility, minimal sample loss, and <15-minute processing time using gravity or centrifugation.
Designed for BigDye® or DyeDeoxy™ terminator removal, as well as buffer exchange and desalting, this gel filtration plate ensures complete and uniform recovery of DNA or RNA across all wells, with clear signal detection starting from the first base.
Performance Highlights
- >99.99% removal of small molecular weight impurities
- Uniform signal intensity from first base in all 96 wells
- Reproducible results across entire plate
- <15-minute processing time
- No centrifugation needed (gravity option)
- Compatible with manual and robotic workflows
Specifications
- Resin: Zetadex-50 Superfine (20–50 µm)
- Format: 96-well microplate (SLAS/ANSI footprint)
- Well Volume: 1000 µL
- Matrix Filling: Uniform gel bed height (visual QC)
- Storage: 4 to 8 °C
- pH Range: 2–13
Applications
- Dye terminator cleanup in DNA sequencing (BigDye®, DyeDeoxy™)
- Oligonucleotide purification
- Desalting of oligonucleotides and nucleic acids
- Buffer exchange prior to downstream processing
- High-throughput sample cleanup for molecular biology labs
Why Choose CentriPure?
CentriPure 96 is engineered to provide clean sequencing reads, consistent sample recovery, and fast processing in a 96-well format. It integrates seamlessly into automated or manual workflows, making it the ideal choice for research labs, genomics facilities, and sequencing providers seeking high-efficiency desalting and contaminant removal.
