Description
Ferrocene-C6-SE – Amine-Reactive Redox Label with 6-Carbon Spacer for Electrochemical Applications
Ferrocene-amidopentyl carboxylic acid NHS ester (Ferrocene-C6-SE) is an amine-reactive ferrocene derivative engineered for covalent attachment to biomolecules via primary amines. Featuring a flexible six-carbon linker, it ensures efficient and reproducible labeling of proteins and alkylamino-modified nucleic acids. Its excellent redox properties make it a powerful marker for biosensor development and other electrochemical applications.
Performance Highlights
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Amine-reactive NHS ester for stable covalent conjugation
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Formal electrode potential: Ef = +0.390 V vs. Ag/AgCl (1 M KCl)
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Contains a 6-carbon spacer for improved accessibility
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Ideal for electrochemical readouts in biosensing platforms
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Validated redox behavior in analytical and diagnostic workflows
Properties
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Trade Name: Ferrocene-amidopentyl carboxylic acid, succinimidyl ester
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Reactive Moiety: NHS ester, reacts with 1° amines to form a stable amide linkage
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Molecular Weight: 440.3
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Empirical Formula: C₂₁H₂₄N₂O₅Fe
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Solubility: DMF, DMSO
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Appearance (color): Orange
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Appearance (form): Solid (powder)
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Storage: −20 °C. Keep dry and protect from light, especially in solution
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CAS Number: None known
Application
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Electroactive labeling of proteins and nucleic acids
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Redox-based detection in biosensor measurements
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Covalent conjugation for electrochemical assays and diagnostics
