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Reliable Moisture Control for Anhydrous Synthesis Workflows

EZ Dry ULTRA Moisture Traps

Precision Drying for Oligonucleotide Synthesis

EZ Dry ULTRA™ moisture traps are designed for high-performance solvent drying in workflows involving oligonucleotide and RNA synthesis. Each sachet contains fully activated molecular sieves enclosed in a chemically inert, solvent-compatible membrane.

The traps consistently maintain moisture levels below 30 ppm, even after multiple container openings. This ensures optimal protection of phosphoramidites, activators, and other moisture-sensitive reagents. Each unit is vacuum-sealed and ready for immediate use—no activation required.

With nine available sizes covering solvent volumes from 100 mL to 20 L, EZ Dry ULTRA supports everything from early-stage R&D to GMP-compliant manufacturing.

Product Highlights

EZ Dry ULTRA™ combines practical features to support clean, consistent, and efficient moisture control:

  • Maintains ≤30 ppm moisture levels in commonly used solvents
  • Vacuum-sealed and pre-activated — ready for immediate use
  • Protects phosphoramidites and activator solutions from hydrolysis
  • Compatible with acetonitrile, pyridine, and toluene
  • Reduces variability and eliminates the need for filtration
  • Manufactured under ISO 9001:2015 quality system
  • Available in sizes for 100 mL to 20 L solvent volumes

Each unit is vacuum-sealed, pre-activated, and manufactured under an ISO 9001:2015 certified quality system.

Product Sizes and Compatibility

 

Choose the correct size based on your container volume and neck diameter:

Trap Size

Solvent Volume

Neck Diameter

Order Number

0.5 g

up to 100 mL

>12 mm

HR-0130-Z001.0-001

1 g

up to 250 mL

>12 mm

HR-0131-Z001.0-001

2 g

up to 500 mL

>12 mm

HR-0132-Z001.0-001

5 g

up to 1 L

>24 mm

HR-0133-Z001.0-001

10 g

up to 2.5 L

>24 mm

HR-0134-Z001.0-001

20 g

up to 4 L

>24 mm

HR-0135-Z001.0-001

25 g

up to 5 L

>24 mm

HR-0136-Z001.0-001

50 g

up to 10 L

>56 mm

HR-0137-Z001.0-001

100 g

up to 20 L

>56 mm

HR-0138-Z001.0-001

All units are vacuum-sealed, pre-activated, and ready to use.

 

Application Areas

EZ Dry ULTRA™ Moisture Traps are used for efficient moisture removal and to maintain anhydrous solvent conditions.
They are particularly suited for:

  • Oligonucleotide and RNA synthesis, where reagents such as phosphoramidites and activators must be protected from hydrolysis
  • Pharmaceutical and diagnostic reagent manufacturing, where solvent stability during storage and use is critical
  • GMP-regulated and quality-sensitive laboratory environments, where reproducibility, cleanliness, and validation are essential
  • High-throughput and automated synthesis workflows, where pre-activated, ready-to-use traps reduce setup time and human error compared to bulk sieves.

Solving Common Challenges in Moisture Control

In workflows like oligonucleotide synthesis, reagent stability depends on maintaining strict low-moisture conditions. Traditional moisture control solutions—such as bulk molecular sieves or membrane-based traps—can fall short due to preparation time, inconsistent performance, or contamination risks. EZ Dry ULTRA™ Moisture Traps provide a ready-to-use, pre-activated solution, batch-tested for consistent drying performance in research and GMP environments.

Time-Consuming Preparation:
Bulk sieves require activation, drying, and careful handling. EZ Dry ULTRA™ is vacuum-sealed and pre-activated — ready for immediate use.

Contamination Risk:
Sieve particles can shed or degrade in solvents. EZ Dry ULTRA’s solvent-resistant sachets keep your system clean and filtration-free.

 

Streamline Your Workflows with EZ Dry ULTRA™

EZ Dry ULTRA™ Moisture Traps combine high-performance drying, contamination control, and ease of use to meet the rigorous demands of pharmaceutical and oligonucleotide synthesis environments. By eliminating particulate risks, reducing variability, and removing the need for additional filtration steps, EZ Dry ULTRA™ simplifies solvent handling while protecting the integrity of your most sensitive reagents. Whether you’re working in early-stage research or GMP-regulated production, EZ Dry ULTRA™ is your clean, consistent, and compliant solution for moisture control.

Start your next project with EZ Dry ULTRA™ and experience clean, reproducible, and hassle-free solvent drying.

Explore the EZ Dry ULTRA™ Range in Our Catalog

Synthesis Reagents for automated oligonucleotide synthesis
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